Photobiomodulation (PBM) is an accurate type of phototherapy including a broad range of nonionizing light sources such as laser, LEDs and broadband visible light in the visible and near infrared spectrum at very low, non-thermal doses.
Mucositis is a serious side effect of cancer therapy. It is defined as inflammatory and/or ulcerative lesions of the oral and/or gastrointestinal tract. Oral mucositis is a serious and acute side-effect for patients undergoing cancer therapy (chemotherapy and/or radiotherapy or target therapy).
Radiation dermatitis is one of the side effects of cancer radiotherapy. Ionizing radiation damages the mitotic ability of stem cells within the basal layer preventing the process of repopulation, weakening the integrity of the skin.
Symptoms include erythema, edema, desquamation and skin ulcers.
Mucositis and radiodermatitis are the most common and most debilitating side effects of chemotherapy and radiotherapy reported by cancer patients.
Despite their frequency, impact on patients quality of life and health and economic costs, there is currently no approved preventive or curative treatment.
Management of these conditions mainly relies on symptom management and prevention of complications, which includes pain control, nutritional support, and prophylaxis / treatment of secondary infections.
CareMin650 is our disruptive solution to tackle this huge unmet clinical need and reduce its societal, emotional and economic burden.
CareMin650 uses photobiomodulation, a scientifically and clinically validated phototherapy for the prevention and treatment of muscositis and dermatitis, which will be comfortable applied through our patented luminous fabric.
Read morePhotobiomodulation is applied clinically in the treatment of soft tissue injuries and accelerated wound healing. The mechanism of photobiomodulation by red to near-IR light at the cellular level has been ascribed by research institutions to the activation of cellular mitochondrial respiratory chain components, resulting in a signaling cascade that promotes cellular proliferation and cytoprotection.
